For more than twenty years, Dr. Melissa Hess Hummel has been helping patients feel better and look their best, both of which often depend on how well they sleep. She is board-certified in both Internal Medicine and Sleep Medicine and treats patients at Three Rivers Medical Associates. For 21 years she has also been Medical Director and physician injector at Rejuvenations Medical Spa in Irmo. Her experience in both sleep and aesthetic medicine has shown her how closely healthy sleep, appearance, and overall well-being are connected.

Her approach is simple: patients deserve to understand what’s going on with their health. She doesn’t believe in just handing over a diagnosis and a prescription. She explains the physiology behind a condition and why she recommends a particular treatment. In her experience, patients who understand the “why” behind her recommendations are the ones who follow through, reach their goals, and ultimately get better.

Dr. Hummel’s training is rooted in South Carolina. She earned her biology degree at the College of Charleston and her medical degree at the University of South Carolina School of Medicine, then completed her Internal Medicine residency at Palmetto Richland Memorial Hospital.

Sleep has been a focus of her career for a long time. She joined the American Academy of Sleep Medicine in 2007 and the South Carolina Sleep Society in 2009. Since then ,she has co-authored a book chapter on circadian rhythm disorders, taken part in clinical research on sleep and circadian health, contributed to continuing medical education, and spoken on sleep and general medical topics. She has also traveled to Nicaragua on medical mission trips.

Dr. Hummel is very grateful to the patients and community members who have voted her a Columbia Metropolitan Premier Physician in 2023, 2025, and again in 2026.